Key result
Complete preservation of the mitral valve apparatus during MVR showed no significant difference in 30-day mortality compared to partial preservation (OR 0.870; 95% CI 0.50-1.52; P=0.63).
Why the study?
Does complete preservation of the mitral valve apparatus improve clinical outcomes compared to partial preservation in patients undergoing mitral valve replacement?
Population
1535 patients undergoing mitral valve replacement (MVR) across 8 studies (2 randomized and 6 non-randomized)
Comparison
Complete preservation of the mitral valve… vs Partial preservation of the mitral valve…
Design
Meta-analysis
Follow-up
up to 5 years
Authors
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No mortality benefit with complete vs partial mitral apparatus preservation during MVR; challenges preference for complete preservation in guidelines and practice.
Meta-Analysis (n=1,535)
Does complete preservation of the mitral valve apparatus improve clinical outcomes compared to partial preservation in patients undergoing mitral valve replacement?
Odds Ratio: 0.87 (95% CI 0.5–1.52)
p-value: p=0.63
Complete preservation of the mitral valve apparatus during mitral valve replacement does not appear to offer superior clinical outcomes compared to partial preservation.
Sá et al. (2013) conducted a meta-analysis in Mitral valve replacement (n=1,535). Complete preservation of mitral valve apparatus vs. Partial preservation of mitral valve apparatus was evaluated on 30-day mortality (OR 0.870, 95% CI 0.50-1.52, p=0.63). Complete preservation of the mitral valve apparatus during MVR showed no significant difference in 30-day mortality compared to partial preservation (OR 0.870; 95% CI 0.50-1.52; P=0.63).
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