Figure 1. Receptor-specific initiation site and propagation pattern of Ca 2+ waves. Cells were sequentially stimulated with 5 M carbachol and 0.25 nM cholecystokinin (CCK), as indicated in the traces in the upper panel. (A) Initiation site and pattern of the Ca 2+ wave evoked by activation of the M3 and CCK receptors in the same cell. (B,C) Additional examples of the different Ca 2+ wave initiation sites evoked by carbachol (white arrowhead) and CCK (magenta arrowhead) stimulation in the same cells.
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Ahuja et al. (2019) studied this question.
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