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October 8, 2025CureusOpen Access

Intraoperative use of dexmedetomidine successfully maintained hemodynamic and rhythm stability in a patient with Wolff-Parkinson-White syndrome undergoing thyroidectomy with bilateral modified neck dissection.

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Why the study?

Perioperative management of WPW syndrome presents significant challenges due to tachyarrhythmia risks under surgical stress, with limited literature regarding thyroid surgeries involving neck dissection.

Design

Case report

Key result

Intraoperative use of dexmedetomidine successfully maintained hemodynamic and rhythm stability in a patient with Wolff-Parkinson-White syndrome undergoing thyroidectomy with bilateral modified neck dissection.

Authors

HRHamood Ur RehmanAAAsma Ashraf

Discussion

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Member takes

Overview

May support dexmedetomidine in WPW neck surgery; hypothesis-generating, needs prospective trials before practice change.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 36-year-old female with asymptomatic Wolff-Parkinson-White syndrome and medullary thyroid carcinoma who underwent total thyroidectomy and bilateral modified neck dissection.
I
Intervention
Perioperative anesthetic management including dexmedetomidine infusion at 0.6 mcg/kg/hour (titrated to maintain heart rate 60-80 bpm and MAP >65 mmHg), propofol induction, sevoflurane maintenance, and avoidance of sympathetic and vagal stimulation.
O
Outcome
Hemodynamic and rhythm stability during the perioperative period.

Dexmedetomidine infusion may be a safe and effective adjunct for maintaining hemodynamic and rhythm stability during high-risk neck surgeries in patients with Wolff-Parkinson-White syndrome.

Limitations

  • Single case report limits generalizability
  • Further research is required to evaluate the efficacy and safety profile of dexmedetomidine in such cases
  • Single case report

Cite This Study

Rehman et al. (2025) conducted a case report in Wolff-Parkinson-White syndrome and medullary thyroid carcinoma (n=1). Dexmedetomidine was evaluated on Hemodynamic and rhythm stability. Intraoperative use of dexmedetomidine successfully maintained hemodynamic and rhythm stability in a patient with Wolff-Parkinson-White syndrome undergoing thyroidectomy with bilateral modified neck dissection.

synapsesocial.com/papers/6a95dc0bfefffbb12b39e248https://doi.org/10.7759/cureus.94165
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dexmedetomidine usage in a patient with pre-excitation syndrome: A case report2024
  2. 2Patient with Wolff-Parkinson-White Syndrome undergoing Non-Cardiac Surgery. Perioperative Management2022
  3. 3Anesthetic Management in a Patient with Wolff-Parkinson-White Syndrome Undergoing Radical Nephrectomy: A Case Report2026
  4. 4Perioperative Management in a Patient with WPW Syndrome undergoing Plastic Surgery.2022
  5. 5Perioperative Management of Patients With Wolff-Parkinson-White Syndrome2026