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January 1, 1997Human Reproduction

Follicular vascularity--the predictive value of transvaginal power Doppler ultrasonography in an in-vitro fertilization programme: a preliminary study

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Authors

DCD. ChuiKingston General HospitalNPNeil PughSt George's, University of LondonSWSamantha WalkerAsthma UK

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Implication

Prospective study reveals higher pregnancy rates from follicles with high vascularity in women undergoing in-vitro fertilization, suggesting follicular blood flow predicts implantation potential.

Key Points

  • To investigate whether follicular vascularity assessed by transvaginal power Doppler ultrasonography correlates with fertilization, pregnancy, and livebirth outcomes during in-vitro fertilization.
  • Assessed 188 individual ovarian follicles in 38 women undergoing in-vitro fertilization using transvaginal power Doppler ultrasound on the day of oocyte retrieval.
  • Graded follicular vascularity on a subjective scale from 1 to 4 and measured pulsatility indices of the uterine and intra-ovarian arteries.
  • Pulsatility indices of the uterine and intra-ovarian arteries showed no significant differences between pregnant and non-pregnant cohorts, and vascularity grade was independent of follicle size.
  • Fertilization rates did not differ significantly by vascularity grade, though a positive trend was observed with higher vascularity.
  • All 10 pregnancies occurred in women receiving embryos derived from follicles with grade 3 (12.5% pregnancy rate per embryo transfer) and grade 4 (61.5%) vascularity, with livebirths occurring exclusively in the grade 4 group.

Cite This Study

Chui et al. (1997) studied this question.

synapsesocial.com/papers/6a95dc9540a936f2a651483fhttps://doi.org/10.1093/humrep/12.1.191
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Contraception: Ovarian stromal blood flow in women with polycystic ovaries—a possible new marker for diagnosis?1995 · 146 citations
  2. 2Transvaginal colour flow imaging of the uterine arteries during the ovarian and menstrual cycles1990 · 201 citations
  3. 3Pregnancies in Humans by Fertilization in Vitro and Embryo Transfer in the Controlled Ovulatory Cycle1981 · 379 citations