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August 20, 2024JAMA

Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy

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Authors

WNWanda K. NicholsonMilken Institute MSMichael SilversteinTufts University JWJohn B. WongTufts University

Discussion

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Implication

Systematic review finds insufficient evidence for screening or routine iron supplementation in asymptomatic pregnant persons, highlighting critical gaps in maternal and infant outcome data.

Key Points

To assess the benefits and harms of screening and routine iron supplementation for iron deficiency and iron deficiency anemia on maternal and infant health outcomes in asymptomatic pregnant persons.
Commissioned systematic review conducted for the US Preventive Services Task Force (USPSTF).
Targeted asymptomatic pregnant adolescents and adults evaluated across all trimesters of pregnancy.
Assessed health outcomes associated with screening and preventative iron supplementation interventions compared with usual care or placebo.
Evidence is insufficient to determine the balance of benefits and harms of screening for iron deficiency and iron deficiency anemia to prevent adverse maternal and infant outcomes (I statement).
Evidence is insufficient to determine the balance of benefits and harms of routine iron supplementation in asymptomatic pregnant individuals on maternal and infant health outcomes (I statement).
Estimated prevalence of iron deficiency increases across pregnancy from 6.9% in the first trimester to 28.4% in the third trimester, with roughly 5% developing iron deficiency anemia.

Cite This Study

Nicholson et al. (2024) studied this question.

synapsesocial.com/papers/6a961a7ec278dbfca3d1bb91 https://doi.org/10.1001/jama.2024.15196

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Implication

Systematic review finds insufficient evidence for screening or routine iron supplementation in asymptomatic pregnant persons, highlighting critical gaps in maternal and infant outcome data.

Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy

Discussion

Member takes

Implication

Key Points

Cite This Study

Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy

Discussion

Member takes

Implication

Key Points

Cite This Study

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