Solvent‐Directed Regioselective Cascade Reaction with Diazo Compounds

This is the authors' abstract. We don't add key points for this paper.

A tandem system comprising cyclization reaction of diazo compound and cross‐coupling of the other one has been developed. This provides facile access to pyrazoles and there derivatives with high levels of regioselectivity in moderate to good yields. This process uniquely utilizes CF3CH2OTf both as a solvent and a catalyst under mild conditions. Mechanistic studies provide insights into the intricate sequence involved in the formation of pyrazoles and further selective cross‐coupling with another diazo compound.