IGL‐1 as a preservation solution in intestinal transplantation: a multicenter experience

This is the authors' abstract. We don't add key points for this paper.

Intestinal transplantation (ITx) is a life-saving procedure for complicated intestinal failure. It is still characterized by a high risk of infection and rejection(1). Of all organs, the intestine is the most vulnerable to ischemia reperfusion injury (IRI) and the associated crosstalk between the innate and adaptive immune response can trigger rejection(2). A crucial factor in limiting IRI is the organ preservation phase. Currently, static cold storage with University of Wisconsin (UW) solution is the gold standard, although other solutions such as HTK (Histidine-Tryptophan-Ketoglutarate) have also been reported (3). Due to low numbers, randomized controlled trials are difficult to organize in this field.