Key result
Big conductance Ca2+-activated K+ channels and L-type voltage-gated Ca2+ channels directly coassemble in certain areas of the rat brain.
Population
Rat brain membranes
Design
Preclinical
Authors
Loading...
Rat brain coassembly data warrant no clinical change; leaves open human relevance in heart or brain.
This study provides evidence for the direct physical coassembly of BK channels and L-type Ca2+ channels in the rat brain, explaining their functional coupling.
Grunnet et al. (2004) studied this question. Big conductance Ca2+-activated K+ channels and L-type voltage-gated Ca2+ channels directly coassemble in certain areas of the rat brain.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: