Key result
Daily home hemodialysis was associated with lower risks of all-cause mortality (HR 0.80; 95% CI 0.73-0.87), hospitalization, and technique failure compared to peritoneal dialysis.
Why the study?
Does daily home hemodialysis reduce mortality, hospitalization, and technique failure compared to peritoneal dialysis in patients with end-stage renal disease?
Population
8,402 new home dialysis patients from the US Renal Data System database
Comparison
Daily home hemodialysis (HHD) vs Matched peritoneal dialysis (PD)
Design
Cohort
Authors
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Daily home hemodialysis was associated with lower mortality than peritoneal dialysis; leaves open confirmation by randomized trials.
Cohort (n=8,402)
Yes
Does daily home hemodialysis reduce mortality, hospitalization, and technique failure compared to peritoneal dialysis in patients with end-stage renal disease?
Hazard Ratio: 0.8 (95% CI 0.73–0.87)
Daily home hemodialysis is associated with decreased mortality, hospitalization, and technique failure compared to peritoneal dialysis, though risks were similar in new dialysis patients.
Weinhandl et al. (2015) conducted a cohort in End-stage renal disease (n=8,402). Daily home hemodialysis vs. Peritoneal dialysis was evaluated on All-cause mortality (HR 0.80, 95% CI 0.73-0.87). Daily home hemodialysis was associated with lower risks of all-cause mortality (HR 0.80; 95% CI 0.73-0.87), hospitalization, and technique failure compared to peritoneal dialysis.