Key result
Patients with acute myocardial infarction had significantly increased mean plasma concentrations of IL-10 (14.9 pg/ml) and IL-6 (18.5 pg/ml) compared to healthy controls (3.4 pg/ml and 0.7 pg/ml, respectively).
Population
20 patients with acute myocardial infarction admitted within 6 hours of symptom onset and 20 healthy…
Design
Case-control
Follow-up
120 hours
Authors
Loading...
IL-10 and IL-6 elevations associated with acute MI; hypothesis-generating for biomarker utility pending prospective validation.
Case-Control (n=40)
No
Absolute Event Rate: 14.9% vs 3.4%
Circulating levels of IL-10 and IL-6 are reciprocally elevated following acute myocardial infarction, with IL-10 potentially serving as a marker of myocardial damage or reperfusion.
Nobuo Kotajima (2001) conducted a case-control in Acute myocardial infarction (n=40). Acute myocardial infarction vs. Healthy controls was evaluated on Mean plasma IL-10 concentration (pg/ml). Patients with acute myocardial infarction had significantly increased mean plasma concentrations of IL-10 (14.9 pg/ml) and IL-6 (18.5 pg/ml) compared to healthy controls (3.4 pg/ml and 0.7 pg/ml, respectively).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: