Key result
Hospitalized pediatric patients experienced substantial polypharmacy, with children ≥1 year at the 90th percentile receiving up to 35 distinct drugs by day 7, especially those with rare conditions (P=0.001).
Cohort (n=587,427)
Yes
p-value: p=0.001
A large fraction of hospitalized pediatric patients are exposed to substantial polypharmacy, particularly those with rare conditions.
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May warrant vigilance for polypharmacy in pediatric hospitalizations; leaves open effects on outcomes and need for targeted strategies.
Chris Feudtner (2011) conducted a cohort in Hospitalized pediatric patients (n=587,427). Polypharmacy was evaluated on Daily and cumulative exposure to drugs and therapeutic agents (p=0.001). Hospitalized pediatric patients experienced substantial polypharmacy, with children ≥1 year at the 90th percentile receiving up to 35 distinct drugs by day 7, especially those with rare conditions (P=0.001).
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