Key result
Primary intracardiac repair resulted in higher pulmonary valve preservation than a systemic-to-pulmonary artery shunt (66% vs 43%, P=0.0098), though infundibular stenosis strongly predicted growth.
Why the study?
This study aimed to determine the effect of the degree of infundibular stenosis on the growth of the pulmonary valve annulus in patients with tetralogy of Fallot.
Does the degree of infundibular stenosis affect the growth of the pulmonary valve annulus in patients with tetralogy of Fallot?
Population
119 patients who underwent ToF repair between 2002 and 2022
Comparison
Systemic-to-pulmonary artery shunt vs primary intracardiac repair
Design
Retrospective cohort study
Authors
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Infundibular index was associated with PV annulus growth independent of SPS; hypothesis-generating for stenosis severity guiding valve preservation in ToF.
Cohort (n=119)
Does the degree of infundibular stenosis affect the growth of the pulmonary valve annulus in patients with tetralogy of Fallot?
Absolute Event Rate: 66% vs 43%
p-value: p=0.0098
The degree of infundibular stenosis is a stronger determinant of pulmonary annular growth than the presence of a systemic-to-pulmonary artery shunt in patients with tetralogy of Fallot.
Kido et al. (2025) conducted a cohort in Tetralogy of Fallot (n=119). Primary intracardiac repair vs. Systemic-to-pulmonary artery shunt was evaluated on Preservation of the pulmonary valve annulus at tetralogy of Fallot repair (p=0.0098). Primary intracardiac repair resulted in higher pulmonary valve preservation than a systemic-to-pulmonary artery shunt (66% vs 43%, P=0.0098), though infundibular stenosis strongly predicted growth.