Key result
Irritable Bowel Syndrome was strongly associated with Generalized Anxiety Disorder in the general population (OR 5.84, P<0.001), and comorbidity added to functional impairment.
Population
2005 participants from a general population
Design
Cross-sectional
Authors
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May support GAD screening in IBS; leaves open causality and whether treatment of one improves the other.
Cross-Sectional (n=2,005)
Odds Ratio: 5.84
p-value: p=< 0.001
IBS and GAD are highly comorbid in the general population, leading to increased functional impairment independent of help-seeking behavior.
Lee et al. (2009) conducted a cross-sectional in Irritable Bowel Syndrome and Generalized Anxiety Disorder (n=2,005). Irritable Bowel Syndrome (IBS) vs. Non-IBS respondents was evaluated on Generalized Anxiety Disorder (GAD) (OR 5.84, p=< 0.001). Irritable Bowel Syndrome was strongly associated with Generalized Anxiety Disorder in the general population (OR 5.84, P<0.001), and comorbidity added to functional impairment.
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