Discovery of a Potent, Orally Active, Nonsteroidal Androgen Receptor Agonist: 4-Ethyl-1,2,3,4-tetrahydro-6- (trifluoromethyl)-8-pyridono[5,6-g]- quinoline (LG121071)

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTDiscovery of a Potent, Orally Active, Nonsteroidal Androgen Receptor Agonist: 4-Ethyl-1,2,3,4-tetrahydro-6- (trifluoromethyl)-8-pyridono[5,6-g]- quinoline (LG121071)Lawrence G. Hamann, Neelakandha S. Mani, Robert L. Davis, Xiao-Ning Wang, Keith B. Marschke, and Todd K. JonesView Author Information Departments of Medicinal Chemistry, Endocrine Research, and New Leads Discovery, Ligand Pharmaceuticals, Inc., 10275 Science Center Drive, San Diego, California 92121. Cite this: J. Med. Chem. 1999, 42, 2, 210–212Publication Date (Web):January 8, 1999Publication History Received24 November 1998Published online8 January 1999Published inissue 1 January 1999https://doi.org/10.1021/jm9806648Copyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views1174Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (62 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Agonists,Antagonists,Assays,Quinolines,Receptors Get e-Alerts