In vitro study reveals biological compatibility of CEM and Biodentine in human dental pulp stem cells, suggesting therapeutic potential for vital pulp therapy.
Key Points
To evaluate the effects of TheraCal-LC, mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM), and Biodentine on the viability, migration, and cytokine secretion of human dental pulp stem cells (hDPSCs).
Assessed hDPSC viability across biomaterial groups using the MTT assay.
Evaluated cell migration capacity with a Transwell migration assay.
Measured chemoattractive cytokine secretion using enzyme-linked immunosorbent assays (ELISA).