Key result
In patients with a normally functioning mechanical pulmonary valve prosthesis, Doppler hemodynamic parameters remained stable between 1 and 4 weeks post-operation, except for pulmonary velocity acceleration time which significantly increased from 87.35 ms to 95.97 ms.
Why the study?
Very few reports have described Doppler-derived echocardiographic parameters for mechanical pulmonary valve prostheses, prompting this study to describe their normal Doppler hemodynamic profile.
Cross-Sectional (n=108)
No
Absolute Event Rate: 95.97% vs 87.35%
p-value: p=0.038
This study establishes normal reference values for Doppler hemodynamics in mechanical pulmonary valve prostheses, aiding in the routine echocardiographic assessment of these patients.
Objectives Very few reports have described the Doppler-derived echocardiographic parameters for mechanical pulmonary valve prosthesis (MPVP). This study aims to describe the normal Doppler hemodynamic profile of MPVP using Doppler echocardiography. Methods The current prospective, single center observational study enrolled 108 patients who underwent pulmonary valve replacement (PVR) surgery for the first time and had a normally functioning prosthesis post-operation. The hemodynamic performance of MPVPs, considering flow dependent and flow independent parameters, was evaluated at two follow-up points, at week one and week four post-operation. All assessments were conducted by an experienced echocardiographer. Results The mean age (±SD) of the participants was 26.4 (±8.98). Tetralogy of Fallot (ToF) was the most common underlying disease leading to PVR, with a prevalence of 88%. At first week post-operation, measurement of indices reported the following values (±SD): peak pressure gradient (PPG): 18.51(±7.64) mm Hg; mean pressure gradient (MPG): 10.88(±5.62) mm Hg; peak velocity (PV): 1.97(±0.43)m/s; doppler velocity index (DVI): 0.61(±18); pulmonary velocity acceleration time (PVAT): 87.35(±15.16) ms; effective orifice area (EOA): 2.98(±1.02) cm2;and effective orifice area to body surface area ratio (EOA/ BSA): 1.81(±0.62) cm2/m2. Comparing these measurements with those obtained from the second follow-up (at week four post-op) failed to hold significant difference in all values except for PVAT, which had increased from its primary value (p = 0.038). Also, right ventricular (RV) function showed significant improvement throughout the follow up period. Conclusion The findings of this study help strengthen the previously scarce data pool and better establish the normal values for Doppler hemodynamics in mechanical pulmonary prosthesis.
No takes yet. Share an insight, caveat, or question.
Shojaeifard et al. (2020) conducted a cross-sectional in Normally functioning mechanical pulmonary valve prosthesis post-replacement (n=108). Mechanical pulmonary valve prosthesis vs. 1-week vs 4-week post-operation follow-up was evaluated on Pulmonary velocity acceleration time (PVAT) (p=0.038). In patients with a normally functioning mechanical pulmonary valve prosthesis, Doppler hemodynamic parameters remained stable between 1 and 4 weeks post-operation, except for pulmonary velocity acceleration time which significantly increased from 87.35 ms to 95.97 ms.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: