Answers are grounded in this paper and cite their sources.
Bromodecarboxylation of the disodium salt of 3,4‐dimethylthiophene‐2,5‐dicarboxylate with bromine in water gave 2,5‐dibromo‐3,4‐dimethylthiophene. This bromodecarboxylation reaction, first mentioned by Melles and Backer (1953), has interesting synthetic aspects and a number of other examples are given.
No takes yet. Share an insight, caveat, or question.
Zwanenburg et al. (1969) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: