Population
48 6-week-old white male New Zealand rabbits (two series of 24 animals)
Comparison
Compression force applied to the right distal… vs Left unloaded femur (internal reference)
Design
Preclinical
Follow-up
up to 2 months
Authors
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Hypothesis-generating for force-dependent physeal arrest; clinical translation to pediatric orthopedics remains untested.
In a rabbit model, applying controlled compression forces to the femoral growth plate proportionally decreases axial growth rate, with forces exceeding 30 N causing rapid growth cessation and cartilage damage.
Bonnel et al. (1983) studied this question.
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