Key result
A 61-year-old man with NSTEMI due to right coronary artery stenosis demonstrated coexistent Takotsubo cardiomyopathy, which resolved four weeks after placement of a drug-eluting stent.
Why the study?
Takotsubo cardiomyopathy typically occurs without obstructive CAD explaining wall motion abnormalities, but increasing evidence suggests acute coronary syndromes may coexist with TCM.
Case Report (n=1)
This case demonstrates that acute coronary syndrome and Takotsubo cardiomyopathy can coexist, suggesting that acute myocardial infarction may act as a physical trigger for Takotsubo cardiomyopathy.
Takotsubo cardiomyopathy (TCM) is characterized by apical ballooning with basal preservation in the absence of obstructive coronary artery disease (CAD) that can otherwise explain wall motion abnormalities. However, there is increasing evidence that acute coronary syndromes (ACSs) may coexist with TCM. This report describes a 61-year-old man with a previous medical history of hypertension, diabetes mellitus, and hyperlipidemia, who presented with acute chest pain and associated shortness of breath. He was diagnosed with a non-ST segment myocardial infarction. Echocardiography revealed impaired systolic function with evidence of apical and periapical ballooning of the left ventricle, characteristic of TCM. Coronary angiography revealed evidence of significant luminal stenosis of the right coronary artery (RCA), necessitating intervention with a drug-eluting stent. This patient demonstrated wall motion abnormalities characteristic of TCM beyond the territory of the affected coronary artery suggesting that CAD and TCM can coexist.
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Ajam et al. (2019) conducted a case report in Takotsubo cardiomyopathy and Non-ST Elevation Myocardial Infarction (n=1). Drug-eluting stent was evaluated on Resolution of wall motion abnormalities and restoration of normal left ventricular ejection fraction. A 61-year-old man with NSTEMI due to right coronary artery stenosis demonstrated coexistent Takotsubo cardiomyopathy, which resolved four weeks after placement of a drug-eluting stent.
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