Key result
Thoracic epidural anaesthesia significantly reduced the incidence of nausea and vomiting compared to general anaesthesia (16.5% vs 39.6%, P=0.02) and resulted in lower immediate pain scores.
Why the study?
Does thoracic epidural anaesthesia improve recovery and analgesia compared to general anaesthesia in patients undergoing MRM?
RCT (n=60)
randomly assigned
Does thoracic epidural anaesthesia improve recovery and analgesia compared to general anaesthesia in patients undergoing MRM?
Absolute Event Rate: 16.5% vs 39.6%
p-value: p=0.02
Thoracic epidural anaesthesia provides better pain management, lower nausea/vomiting, and higher patient satisfaction compared to general anaesthesia for MRM surgeries.
TEA should be considered over GA for MRM to optimize recovery; extends RCT support for regional anesthesia in breast cancer surgery.
Background : General anaesthesia is still the preferred technique amongst many practitioners for oncologic breast surgeries. However the TEA technique has a lot of advantages over the conventional GA technique. Objective: We attempted to evaluate the two techniques of anaesthesia for MRM surgeries. Materials and Method: Sixty ASA I-II patients undergoing MRM were randomly assigned to two study groups of 30 patients each. In the TEA group (group T), an epidural catheter was inserted at T7-T8 level, and 8-10 ml of 0.5% bupivacaine was titrated and administered. GA (group G) was induced with 2mg/kg of propofol and was maintained with Isoflurane, intermittent inj. Vecuronium and 70% N2O in oxygen. The authors evaluated the adequacy of anesthesia, surgical condition, post anesthetic recovery, post anesthetic analgesia and patients' satisfaction. Results: The intra operative haemodynamics was comparable in between the two groups. The incidence of nausea and vomiting was significantly lower in the TEA group (16.5% in group T and 39.6% in group G , P = 0.02). The mean immediate VAS score was also lower in TEA group ( group T =2.4 , group G =5.8,P = 0.001). Aldrete recovery score was 9/10 in 1 st hr in a significant proportion in the TEA group (89.1% in group T v/s 59.4% in group G , P = 0.003). Patient satisfaction was significantly higher. The surgeons were however satisfied with both the methods. Conclusion: Use of thoracic epidural technique as a sole anaesthetic technique for MRM surgeries provides adequate operating conditions, better side effect profile, better pain management and patient satisfaction.
No takes yet. Share an insight, caveat, or question.
Sujata Lahiry (2016) conducted an RCT in Oncologic breast surgeries (MRM) (n=60). Thoracic Epidural Anaesthesia (TEA) vs. General Anaesthesia (GA) was evaluated on Incidence of nausea and vomiting (p=0.02). Thoracic epidural anaesthesia significantly reduced the incidence of nausea and vomiting compared to general anaesthesia (16.5% vs 39.6%, P=0.02) and resulted in lower immediate pain scores.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: