Answers are grounded in this paper and cite their sources.
ONNE OF THE MOST IMPORTANT PROBLEMS confronting the clinical physiologist today is how the stomach makes its hydrochloric acid. Nowhere else in the body does a physiological fluid regularly attain a pH less than 3.0, let alone a value between 0.8 and 0.9 of a pH unit. Formation of such a solution requires the liberation of a strong acid, at concentration of about 0.17 N. This process has always fascinated me because of the simplicity of the chemical entity involved, but my interest in the problem derives from utilitarian clinical considerations as well. Some fifteen years ago, Dr. Alvarez of the Mayo Clinic said that the unequivocal cure of gastrointestinal ulceration awaits a medical procedure based on the complete elimination of acid formation in the stomach, and in order to attain this it is necessary that
No takes yet. Share an insight, caveat, or question.
Franklin Hollander (1949) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: