Key result
Echocardiographic assessment of end-systolic indices in dialysis patients is confounded by altered loading conditions and reflex sympathetic activity, requiring further validation before uncritical use.
Population
Uraemic/dialysis patients
Design
Review
Authors
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Caution against uncritical use of end-systolic indices in dialysis patients; leaves open their validity pending load-adjusted validation.
Echocardiographic end-systolic indices may not provide a truly load-independent assessment of intrinsic cardiac contractility in dialysis patients due to altered loading conditions and reflex sympathetic activity.
Charles Tomson (1990) conducted a review in Uraemia / Dialysis. Echocardiographic assessment of end-systolic indices was evaluated. Echocardiographic assessment of end-systolic indices in dialysis patients is confounded by altered loading conditions and reflex sympathetic activity, requiring further validation before uncritical use.
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