Key result
Metabolic syndrome was associated with a 10-fold higher risk of coronary artery disease among Thai physicians (47.2% vs 7.9%; OR 10.41; 95% CI 6.70-16.16; P<0.001).
Why the study?
Physicians may be at risk for metabolic syndrome due to work and lifestyle patterns, but its prevalence and association with coronary artery disease among them required evaluation.
Is metabolic syndrome associated with an increased risk of coronary artery disease among physicians?
Cross-Sectional (n=1,194)
No
Is metabolic syndrome associated with an increased risk of coronary artery disease among physicians?
Odds Ratio: 10.41 (95% CI 6.7–16.16)
Absolute Event Rate: 47.2% vs 7.9%
p-value: p=<0.001
Metabolic syndrome is present in nearly 9% of Thai physicians and is associated with a 10-fold higher odds of coronary artery disease.
MetS signals markedly elevated CAD odds in physicians; extends prior associations but leaves open causal links and intervention effects.
Background: Physicians, due to their work and lifestyle patterns, can be at risk for metabolic syndrome (MetS). We aimed to evaluate the prevalence of MetS among physicians and its association with coronary artery disease (CAD). Materials and methods: This retrospective cross-sectional study collected data on Thai physicians who had medical examination including cardiovascular testing from 14 February to 31 October 2022, in our hospital. Inclusion criteria were those who had complete data for MetS diagnosis per Adult Treatment Panel III criteria and CAD diagnosis information. Outcome measures were prevalence of MetS and CAD prevalence in affected vs non-affected physicians. Results: Of 1194 physicians, the median age was 48.0±10.29 years. The authors found 4.5% were obese, 30.6% having high blood pressure, 26.6% high fasting blood sugar (FBS), 12.7% high triglycerides, and 13.7% low high-density lipoprotein (HDL). The prevalence of MetS was 8.9%. Increasing age, systolic blood pressure, body mass index, FBS, triglyceride, and decreasing HDL were identified as independent risk factors of MetS. The prevalence of CAD was 11.4%: 47.2% vs. 7.9% among the physicians with and without MetS respectively (odds ratio 10.41: 95% CI, 6.70–16.16%, P<0.001). Conclusion: The prevalence of MetS among Thai physicians in this study was 8.9%. Those physicians with MetS were associated with a 10-fold higher risk of CAD. Physicians who were at risk of developing MetS should consider modifying their health habits and being vigilant about the potential consequences of CAD. Further prospective cohort studies are warranted to validate these results.
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Tangjitgamol et al. (2023) conducted a cross-sectional in Metabolic syndrome and coronary artery disease (n=1,194). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Prevalence of coronary artery disease (OR 10.41, 95% CI 6.70-16.16, p=<0.001). Metabolic syndrome was associated with a 10-fold higher risk of coronary artery disease among Thai physicians (47.2% vs 7.9%; OR 10.41; 95% CI 6.70-16.16; P<0.001).
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