Why the study?
Understanding heterogeneity in chronic kidney disease prognosis has management implications, motivating an evaluation of the comparative risk of ESKD, CV events, and death among CKD patients in China.
Population
3,700 patients with CKD stage 1–4 from 39 clinical centers in China
Design
Multicenter prospective cohort study
Follow-up
Median 4.65 to 4.84 years across outcomes
Key result
In Chinese patients with stage 1-4 chronic kidney disease, the incidence of end-stage kidney disease was significantly higher than that of cardiovascular events, with an incidence ratio of 2.15.
Authors
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ESKD predominates over CV events and death in Chinese CKD stages 1–4; extends heterogeneity data but leaves open generalizability and practice implications.
Cohort (n=3,700)
Yes
Relative Risk: 2.15 (95% CI 1.87–2.53)
Absolute Event Rate: 3.1% vs 1.5%
In Chinese patients with stage 1-4 CKD, the risk of progressing to end-stage kidney disease is significantly higher than the risk of cardiovascular events or death.
Wang et al. (2021) conducted a cohort in Chronic Kidney Disease (n=3,700). Stage 1-4 chronic kidney disease was evaluated on Ratio of incidence of ESKD to cardiovascular events (Incidence ratio 2.15, 95% CI 1.87, 2.53). In Chinese patients with stage 1-4 chronic kidney disease, the incidence of end-stage kidney disease was significantly higher than that of cardiovascular events, with an incidence ratio of 2.15.
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