Fibroblast growth factor injected into denervated early regenerates of adult newt forelimbs promotes mitotic activity in the dedifferentiated mesodermal cells. The effect is dose‐dependent and is not produced with similar doses of cytochrome c, bovine serum albumin, or growth hormone. Epidermal growth factor has a mitogenic effect less than half as great as that of fibroblast growth factor. The results suggest the possibility of a role for myel in‐derived growth factors in blastema formation.
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Mescher et al. (1979) studied this question.
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