Why the study?
Refractory epilepsy remains frequent despite medical therapies, and vagus nerve stimulation offers neuromodulation that carries anesthetic management risks and physiological implications.
Cross-Sectional (n=40)
No
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Vagus nerve stimulation is a neuromodulation option for refractory epilepsy that requires anesthesiologists to anticipate and manage specific physiological implications and potential complications.
Epilepsy is defined as a neurological disorder manifested by an excessive and abnormal electrical neuronal discharge. Refractory epilepsy still remains quite frequent condition, considered 30-40% of all patients with seizures, despite improvement in medication possibilities. Vagus Nerve Stimulator offers a neuromodulation approach when other treatment possibilities are exhausted. This minor procedure is safe but carries potential risks for anesthetic management and anesthesiologists should be aware of the physiological implications of the device and anticipate and manage possible complications.
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Delova et al. (2025) conducted a cross-sectional in Cervical dysplasia (n=40). p16/Ki67 dual immunocytochemistry staining vs. Liquid-Based Cytology (LBC) was evaluated on Association between High-Grade Squamous Intraepithelial Lesion (HSIL) and p16/Ki67 dual staining (p=0.012).
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