Key result
QRS duration significantly correlated with right ventricular ejection fraction (r = -0.61) and volumes in early-operated patients with repaired tetralogy of Fallot, but not late-operated patients.
Why the study?
In patients after complete repair of tetralogy of Fallot, QRS duration is associated with right ventricular size and mechanical function, but the utility of routine electrocardiography relative to CMR needed clarification.
Does 24 h ambulatory electrocardiography monitoring correlate with right ventricular morphology and function assessed by CMR in patients with repaired tetralogy of Fallot?
Observational (n=38)
Does 24 h ambulatory electrocardiography monitoring correlate with right ventricular morphology and function assessed by CMR in patients with repaired tetralogy of Fallot?
Effect estimate: r = -0.61
Electrocardiography has a limited role as a predictor of right ventricular morphology and function in patients after repair of tetralogy of Fallot, particularly in late-operated patients.
BACKGROUND: In patients following complete repair of the tetralogy of Fallot, the duration of the QRS complex is associated with the size and mechanical function of the right ventricle, which are contemporarily assessed by cardiac magnetic resonance (CMR). METHODS: 38 patients aged 18.0-54.9 years (median age 24.9 years) who had undergone complete repair of the tetralogy of Fallot were examined using CMR and concomitant 24 h ambulatory electrocardiography monitoring. We used statistical analysis to investigate the correlations between electrocardiographic parameters (heart rate, HR; PQ interval, PQ; QRS duration, QRS; and corrected QT interval, QTc) and CMR results (right ventricular ejection fraction, RVEF; right ventricular end-diastolic volume index, RVEDVI; and right ventricular end-systolic volume index, RVESVI) for patients after early and late repair. RESULTS: The ECG-based parameters were not correlated with time since repair. There were significant correlations between QRS duration and RVEF (r = -0.61), RVEDVI (r = 0.56), and RVESVI (r = 0.54) for early operated patients but not for late-operated patients. No other substantial correlations were reported. CONCLUSION: Despite its role in screening for arrhythmias, electrocardiography has a limited role as a predictor of morphology and function of the right ventricle in patients after repair of the tetralogy of Fallot.
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Lubocka et al. (2021) conducted an observational in Repaired tetralogy of Fallot (n=38). Electrocardiography (QRS duration) was evaluated on Correlation between QRS duration and right ventricular ejection fraction (RVEF) (r = -0.61). QRS duration significantly correlated with right ventricular ejection fraction (r = -0.61) and volumes in early-operated patients with repaired tetralogy of Fallot, but not late-operated patients.
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