Adenine base editor incorporating the N-methylpurine DNA glycosylase MPGv3 enables efficient A-to-K base editing in rice

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of the base-editing efficiencies of rBE118 and rBE120 at tested genomic sites in transgenic rice lines.(E) Efficiencies of A-to-T/C editing by rBE118 and rBE120 across the protospacer positions 1-12 (where the PAM is at positions 21-23) from the A-to-G edited sites in (B) and (D).Each dot represents the A-to-T/C editing efficiency of an independent NAN motif.(F) Diagram showing 12 types of site-specific point mutations that can be achieved with available base editors in rice.