Report of an Outbreak of Q Fever at the National Institute of Health. I. Clinical Features

Article1 July 1947REPORT OF AN OUTBREAK OF Q FEVER AT THE NATIONAL INSTITUTE OF HEALTH. I. CLINICAL FEATURESCHARLES G. SPICKNALL, M.D., ROBERT J. HUEBNER, M.D., JAMES A. FINGER, M.D., WILLIAM P. BLOCKER, M.D.CHARLES G. SPICKNALL, M.D.Search for more papers by this author, ROBERT J. HUEBNER, M.D.Search for more papers by this author, JAMES A. FINGER, M.D.Search for more papers by this author, WILLIAM P. BLOCKER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-1-28 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAt the end of the first week of February 1946, a febrile illness began to appear among the workers in Building No. 5* of the National Institute of Health where research was being done on the rickettsia of Q fever. Eighteen cases occurred in an explosive manner between February 6 and February 11, 1946. By May 31 the total number of cases reached 47. This paper deals with the clinical characteristics shown by 45 of the 47 cases.Epidemiological1and laboratory2aspects of the outbreak are considered in the other papers in this series. The recent report of a number...Bibliography1. HUEBNER RJ: Report of an outbreak of Q fever at the National Institute of Health. II. Epidemiological features. (To be published.) Google Scholar2. HUEBNERDUBUY RJH: Report of an outbreak of Q fever at the National Institute of Health. III. Laboratory and certain experimental epidemiological features. (To be published.) Google Scholar3. IRONSTOPPINGSHEPARDCOX JVNHCCHR: Outbreak of Q fever in the United States, Pub. Health Rep., 1946, lxi, 784-785. CrossrefGoogle Scholar4. ROBBINSRAGAN FCCA: Q fever in the Mediterranean area: Report of its occurrence in American troops. I. Clinical features of the disease, Am. Jr. Hyg., 1946, xliv, 6-22. Google Scholar5. . 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HORNIBROOKNELSON JWKR: An institutional outbreak of pneumonitis. Epidemiological and clinical studies, Pub. Health Rep., 1940, lv, 1936. CrossrefGoogle Scholar18. DYERTOPPINGBENGTSON RENHIA: An institutional outbreak of pneumonitis, isolation and identification of causal organism, Pub. Health Rep., 1940, lv, 1946. Google Scholar19. LILLIEPERRINARMSTRONG RDTLC: An institutional outbreak of pneumonitis. Histopathology in man and rhesus monkeys in the pneumonitis due to the virus of Q fever, Public Health Rep., 1941, lvi, 149-155. CrossrefGoogle Scholar20. BENGTSON IA: Complement fixation in rickettsial diseases. Technique of test, Pub. Health Rep., 1944, lix, 402-405. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 9, 1946.From the National Institute of Health, Bethesda, Maryland, and The U. S. Public Health Service Dispensary, Washington, D. C.†Surgeon, U. S. Public Health Service.‡Senior Assistant Surgeon, U. S. Public Health Service.§Assistant Surgeon, U. S. Public Health Service.*Building No. 5 is one of 8 buildings which house the Bethesda laboratories of the National Institute of Health. In this building are the Division of Infectious Diseases, Division of Biologics Control, and a dental unit of the Division of Physiology. 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