A single photometric detector can accurately measure in vivo pulsatile blood velocity in microvessels, matching the performance of dual-detector cross-correlation techniques.
Simplifies microvessel velocity assessment; leaves open clinical translation pending prospective validation.
A method for the in vivo detection of pulsatile blood velocity in transilluminated microvessels using data contained in single photometric signals is described. The system design is based on the assumption that pulsatile velocity information is contained in frequency- modulated components of the photometric signal spectrum. Results are in agreement with a previously reported cross-correlation technique utilized to measure the time delay between signals from upstream and downstream photodetectors aligned in the direction of flow.
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Silva et al. (1973) studied this question.
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