Why the study?
Flow obstruction causes uninterpretable results on the Platelet function analyzer-200, so researchers investigated whether closure curves and research parameters allow detection of clopidogrel effects in these cases.
Can numerical parameters and visual curve analysis of PFA-200 detect the effect of clopidogrel in flow-obstructed feline blood samples?
Population
Closure curves from cats evaluated for clopidogrel effects
Comparison
Flow-obstructed curves vs paired non-flow-obstructed curves
Design
Retrospective review with blinded visual analysis
Authors
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May aid obstructed PFA-200 interpretation in cats; leaves open need for validation before clinical use.
Can numerical parameters and visual curve analysis of PFA-200 detect the effect of clopidogrel in flow-obstructed feline blood samples?
Numerical parameters from the PFA-200 can accurately detect clopidogrel effects in flow-obstructed feline blood samples, whereas visual curve analysis cannot.
Kornya et al. (2023) studied this question.
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