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Thyrotoxic hypokalemic periodic paralysis is a reversible but profound complication of thyrotoxicosis requiring cautious treatment to avoid rebound hyperkalemia.
Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare but potentially serious complication of thyrotoxicosis. The resulting muscle weakness is profound, associated with more severe hypokalemia, yet reversible. However, clinicians must be cautious because patients can develop life-threatening hyperkalemia during treatment. Underlying causes should be investigated as repeated episodes of THPP may occur.
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Patel et al. (2017) studied this question.
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