Intraperitoneal and abdominal wall infiltration with bupivacaine plus tramadol and tenoxicam after total abdominal hysterectomy provides analgesia

Background: The aim of our study was to assess the effect of intraperitoneal and abdominal wall infiltration with bupivacaine plus tramadol and tenoxicam after total abdominal hysterectomy. Methods: Sixty patients who have undergone abdominal hysterectomy were allocated randomly to three different groups: group I (bupivacaine + tramadol): 20 patients infiltrated with 40 ml 0.25% bupivacaine plus 100 mg tramadol; group II (bupivacaine + tenoxicam): 20 patients infiltrated with 40 ml 0.25% bupivacaine plus 20 mg tenoxicam; and group III (bupivacaine + tramadol + tenoxicam): 20 patients infiltrated with 40 ml 0.25% bupivacaine + 100 mg tramadol + 20 mg tenoxicam. The intraperitoneal and abdominal wall infiltration was done to each patient after hysterectomy. The study was performed in a double-blind controlled manner. Results: In group III, pain scores (VAS) and analgesic requirement (tramadol) during the 24 h after surgery were significantly lower than in groups I and II. Tramadol requirements after the operation were similar in groups I and II. Pain scores, were similar in groups I and II. Side effects and recovery variables were similar in all groups.