Key result
Phonocardiographic assessment using the Wells' index failed to accurately predict mitral valve area compared to catheterization and surgical data in all 6 patients with mitral stenosis.
Why the study?
Does phonocardiography accurately predict mitral valve area compared to cardiac catheterization and surgery in patients with mitral stenosis?
Case Report (n=6)
Does phonocardiography accurately predict mitral valve area compared to cardiac catheterization and surgery in patients with mitral stenosis?
The Wells' index derived from phonocardiography is not an absolute criterion for the severity of mitral stenosis, as it can be altered by factors other than pressure changes such as flow, valve stiffness, and regurgitation.
Phonocardiography with Wells' index warrants caution in mitral stenosis; leaves open its diagnostic role versus invasive measures.
Phonocardiographic, cardiac catheterization and surgical data are analyzed and compared for six patients exhibiting mitral stenosis whose phonocardiographic findings failed to predict the mitral valve area as estimated by the other two methods. The corrected Wells' indices (Q1 minus 2 OS times) ranged from -5 to +1 and were discrepant to actual valve size in all six patients. Analysis of Q1 and 2 OS intervals usually permits a reasonable estimate of the degree of stenosis of the mitral valve. However, the intervals are altered primarily by pressure changes. Alterations of other factors such as flow, valve stiffness, and regurgitation may result in discrepancies of these measurements. As demonstrated in these patients, the Wells' index is not an absolute criterion of the severity of mitral stenosis.
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Charles E. Rackley (1968) conducted a case report in Mitral stenosis (n=6). Phonocardiographic assessment (Wells' index) vs. Cardiac catheterization and surgical data was evaluated on Prediction of mitral valve area. Phonocardiographic assessment using the Wells' index failed to accurately predict mitral valve area compared to catheterization and surgical data in all 6 patients with mitral stenosis.
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