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November 1, 1994BloodOpen Access

Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector

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Authors

Christof von KalleChristof von KalleNorthwestern UniversityHKHP KiemSeattle Cancer Care AllianceSGSondra GoehleCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

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Kalle et al. (1994) studied this question.

synapsesocial.com/papers/6a9699caff8a6b2115f6b5b0https://doi.org/10.1182/blood.v84.9.2890.2890
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells.1989 · 308 citations
  2. 2Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures1993 · 19 citations
  3. 3Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.1986 · 825 citations
  4. 4Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells1990 · 8 citations