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August 1, 1986Molecular and Cellular Biology

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

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Authors

AMA. Dusty MillerBrigham Young UniversityCBC ButtimoreFred Hutch Cancer Center

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Miller et al. (1986) studied this question.

synapsesocial.com/papers/6a17323ceae9613b5fbde71dhttps://doi.org/10.1128/mcb.6.8.2895
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Retroviral transfer of genes into canine hemopoietic progenitor cells in culture: a model for human gene therapy.1986 · 82 citations
  2. 2Generation of Helper-Free Amphotropic Retroviruses That Transduce a Dominant-Acting, Methotrexate-Resistant Dihydrofolate Reductase Gene1985 · 128 citations
  3. 3High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.1984 · 406 citations