Key result
Blunt chest trauma was associated with significantly higher Tp-e/QT (0.23 vs. 0.19) and Tp-e/QTc (0.21 vs. 0.17) ratios compared to healthy controls, indicating increased risk for cardiac arrhythmia.
Why the study?
Potentially destructive arrhythmias can develop after blunt chest trauma, but the value of Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio as risk markers required evaluation.
Are the Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio elevated in patients with blunt chest trauma compared to controls?
Case-Control (n=98)
No
Are the Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio elevated in patients with blunt chest trauma compared to controls?
Absolute Event Rate: 0.23% vs 0.19%
p-value: p=<0.001
Tp-e/QT and Tp-e/QTc ratios are significantly elevated in patients with blunt chest trauma, suggesting they may serve as potential markers for arrhythmia risk.
May flag arrhythmia risk in blunt chest trauma; hypothesis-generating for Tp-e/QT ratios pending prospective validation.
Objective: Diffirents complications can develop after blunt chest trauma. It has been shown that potentially dectructive arrhythmias may develop after blunt chest trauma. In this study, our main objective is to evaluate the risk of cardiac arrhythmia in patients with blunt chest trauma, using the Tp-e interval, tp-e/QT ratio, and Tp-e/QTc ratio as a potential marker of cardiac arrhythmia. Materials and Methods: Our study consists of all patients who applied to the emergency department with blunt chest trauma between 15.01.2022 and 15.06.2022 in the form of a single-center, prospective case-control. 12-lead ECG documented on were taken from all participants at a paper speed of 50 mm/sec, and Tp-e interval, QT interval and the parameters obtained by their ratio to each other (tp-e/QT, Tp-e/QTc) were compared between the groups. Patients were shared according to trauma severity and parameters were compared. Results: Tpe/QT ratio in trauma patients was found to be statistically significantly higher than the control group (0.23±0.03 vs. 0.19±0.03, p<0.001). In addition, the Tpe/QTc ratio in trauma patients was found to be statistically significantly higher than the control group (0.21±0.02 vs. 0.17±0.02, p<0.001). In addition, when the analysis of age, gender and BMI, which are the factors affecting trauma severity, was performed, no significant difference was found in terms of QT interval, Tp-e/QT and Tp-e/QTc. Conclusıon: Based on the results of our study, we verified that the Tp-e interval in the ECG, Tp-e/QT ratio, and Tp-e/QTc ratio might indicate possible arrhythmia in patients who presented to the emergency department with blunt thoracic trauma, and this was unrelated to the severity of the trauma.
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Yıldız et al. (2023) conducted a case-control in Blunt chest trauma (n=98). Blunt chest trauma vs. Healthy volunteers was evaluated on Tp-e/QT ratio (p=<0.001). Blunt chest trauma was associated with significantly higher Tp-e/QT (0.23 vs. 0.19) and Tp-e/QTc (0.21 vs. 0.17) ratios compared to healthy controls, indicating increased risk for cardiac arrhythmia.
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