Key result
Two cases of maternal floor infarction occurred in fetuses with oligohydramnios resulting from bilateral cystic renal dysplasia, suggesting fetoplacental factors may play a role in MFI.
Case Report (n=2)
This case report suggests a potential fetal basis for maternal floor infarction, possibly involving changes in intrauterine hydrostatic pressure gradients due to oligohydramnios.
Maternal floor infarction (MFI) is an unusual, idiopathic placental disorder characterized by deposition of amorphous fibrinoid material along the maternal aspect of the intervillous space. This condition is associated with poor perinatal outcome-in particular, spontaneous abortion-fetal growth restriction, and stillbirth, with a high recurrence rate in subsequent pregnancies. It is unknown whether MFI is a single entity or the common end point of different insults. Most studies have linked MFI to underlying maternal disorders including gestational hypertension, autoimmune disease, and thrombophilia. In contrast, there have been only a few case reports regarding the possibility of a fetal basis for MFI. We report 2 cases of MFI in fetuses who suffered from oligohydramnios as a result of bilateral cystic renal dysplasia. These 2 cases suggest the concept that fetoplacental factors may also play a role in MFI. It is speculated that the mechanism might involve changes in intrauterine hydrostatic pressure gradients.
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Taweevisit et al. (2009) conducted a case report in Maternal floor infarction (n=2). Oligohydramnios and bilateral cystic renal dysplasia was evaluated on Maternal floor infarction. Two cases of maternal floor infarction occurred in fetuses with oligohydramnios resulting from bilateral cystic renal dysplasia, suggesting fetoplacental factors may play a role in MFI.
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