Key result
Three pregnancies in patients with primary antiphospholipid antibody syndrome treated with low-dose aspirin and heparin were complicated by massive perivillous fibrous deposition and maternal floor infarction.
Population
3 pregnancies in patients with primary antiphospholipid antibody syndrome attending a recurrent miscarriage…
Design
Case_series
Authors
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Primary APS may predispose to MPVFD/MFI despite aspirin/heparin; hypothesis-generating, needs confirmation in larger studies.
Case Report (n=3)
Primary antiphospholipid antibody syndrome may predispose patients to massive perivillous fibrous deposition and maternal floor infarction despite treatment with aspirin and heparin.
Sebire et al. (2002) conducted a case report in Primary antiphospholipid antibody syndrome (PAPS) in pregnancy (n=3). Low dose aspirin and heparin was evaluated on Massive perivillous fibrous deposition (MPVFD) and maternal floor infarction (MFI). Three pregnancies in patients with primary antiphospholipid antibody syndrome treated with low-dose aspirin and heparin were complicated by massive perivillous fibrous deposition and maternal floor infarction.
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