Key result
2D RV average free wall longitudinal strain at a cutoff ≥ -19.7% independently predicted proximal RCA culprit lesions with 91.7% sensitivity and 70.5% specificity (OR 37.75, P=0.036).
Why the study?
Can 2D RV average free wall longitudinal strain predict proximal RCA culprit lesions in patients with acute inferior MI?
Observational (n=68)
Can 2D RV average free wall longitudinal strain predict proximal RCA culprit lesions in patients with acute inferior MI?
Odds Ratio: 37.75
p-value: p=0.036
2D RV average FWLS is a useful tool for diagnosing RV involvement and predicting proximal RCA culprit lesions in patients with acute inferior MI.
May support RV strain for proximal RCA prediction in inferior MI; hypothesis-generating pending prospective validation.
BACKGROUND: It is important to diagnose right ventricular (RV) infarction in the setting of acute inferior myocardial infarction (MI). We aimed to improve the diagnostic accuracy of RV infarction and identify a high-risk subset of inferior MI patients with proximal RCA lesions. HYPOTHESIS: We tried to find the link between speckle tracking and coronaries in high risk inferior infarction METHODS: This study included 68 patients within 24 hours of first acute inferior MI. Group 1 (n = 49) isolated inferior MI; group 2 (n = 19) inferior and RV MI. echocardiography for RV free wall longitudinal strain (FWLS), RV fractional area change (FAC), tricuspid annular plane systolic excursion (TAPSE), RV myocardial performance index (MPI) and peak systolic velocity (S'). RESULTS: Group 2 had higher MPI by tissue Doppler and 2D-RV average FWLS, whereas RV FAC, S', and TAPSE were lower (P < 0.001). In group 1, 14.4% had a significant proximal RCA lesion with impaired RV function. RV average FWLS at a cutoff value ≥ - 19.7% can predict proximal RCA culprit lesion with 91.7% sensitivity and 70.5% specificity, which was detected as an independent predictor in multivariate logistic regression (odds ratio: 37.75, P = 0.036). CONCLUSIONS: 2D RV average FWLS at a cutoff of ≥ - 19.7% is a useful added tool for diagnosis of RV involvement and an independent predictor to rule in proximal RCA culprit lesion in inferior-wall MI patients in the emergency department.
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Roshdy et al. (2018) conducted an observational in acute inferior myocardial infarction (n=68). 2D RV average free wall longitudinal strain (FWLS) was evaluated on proximal RCA culprit lesion (OR 37.75, p=0.036). 2D RV average free wall longitudinal strain at a cutoff ≥ -19.7% independently predicted proximal RCA culprit lesions with 91.7% sensitivity and 70.5% specificity (OR 37.75, P=0.036).
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