Key result
Pentaborane exposure in 14 individuals led to worsening neuropsychiatric status at 18 months, with PTSD, major affective disorder, alcohol abuse, and phobias being the most common diagnoses.
Why the study?
What are the long-term neuropsychiatric effects of pentaborane intoxication?
Observational (n=14)
What are the long-term neuropsychiatric effects of pentaborane intoxication?
Brief exposure to pentaborane is associated with significant long-term neuropsychiatric morbidity at 18 months.
May warrant neuropsychiatric monitoring after pentaborane exposure; hypothesis-generating and requires prospective validation.
Fourteen individuals briefly exposed to the neurotoxic compound Pentaborane were reevaluated 18 months following initial neurpsychiatric study. Psychiatric interview utilizing standardized diagnostic criteria, neuropsychological and psychological assessment, and CT scan ventricular brain ratios were reevaluated. Assessment revealed interaction of bilogical and psychological factors worsening. Post‐traumatic stress disorder, major affective disorder, alcohol abuse, and phobias were the most common diagnoses at follow‐up.
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Silverman et al. (1989) conducted an observational in Pentaborane intoxication (n=14). Pentaborane exposure was evaluated on Neuropsychiatric effects including psychiatric diagnoses, neuropsychological assessment, and CT scan ventricular brain ratios. Pentaborane exposure in 14 individuals led to worsening neuropsychiatric status at 18 months, with PTSD, major affective disorder, alcohol abuse, and phobias being the most common diagnoses.
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