Key result
Brown adipose tissue plays a role in the pathogenesis of polycystic ovary syndrome, and its transplantation in rat models has been shown to significantly alleviate PCOS phenotypes.
Brown adipose tissue may play a role in the pathogenesis of PCOS and holds promise as a target for its prevention and treatment.
Brown adipose tissue (BAT) holds great promise for the prevention and treatment of metabolism diseases through thermoregulation. Polycystic ovary syndrome (PCOS) is a complex condition with anovulation, hyperandrogenism, and polycystic ovaries, and also manifests glucolipid metabolic disorders. Recent researches have shown that transplantation of BAT into a PCOS rat could significantly alleviate the phenotypes. This article reviews the role of BAT in pathogenesis of PCOS, which may provide information for prevention and treatment of PCOS.
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Fu et al. (2017) conducted a review in Polycystic ovary syndrome (PCOS). Brown adipose tissue (BAT) was evaluated. Brown adipose tissue plays a role in the pathogenesis of polycystic ovary syndrome, and its transplantation in rat models has been shown to significantly alleviate PCOS phenotypes.
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