Key result
A 4-year and 10-month-old girl developed florid myasthenia gravis after thoracotomy for the removal of a thymoma, demonstrating that this association can occur in childhood.
Case Report (n=1)
This case demonstrates that the association between thymoma and myasthenia gravis can occur in early childhood, contrary to previous reports.
Myasthenia gravis may occur after pediatric thymoma resection; extends the association to early childhood but remains hypothesis-generating.
Thymomas are exceedingly rare in the first 20 years of life, and only a few well-documented cases are present in the literature. Thymomas in adults are commonly associated with other diseases, the most frequent being myasthenia gravis (MG). However, this association has been reported not to occur in childhood. The authors report the case of a 4-year and 10-month-old girl who presented with clinical evidence of MG before thoracotomy and who developed florid MG after thoracotomy for removal of an anterior mediastinal mass later documented to be a thymoma.
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Furman et al. (1985) conducted a case report in Thymoma and myasthenia gravis (n=1). Thoracotomy for removal of an anterior mediastinal mass was evaluated on Development of florid myasthenia gravis. A 4-year and 10-month-old girl developed florid myasthenia gravis after thoracotomy for the removal of a thymoma, demonstrating that this association can occur in childhood.
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