Impact of Preeclampsia on Clinical and Functional Outcomes in Women With Peripartum Cardiomyopathy
Key result
In women with peripartum cardiomyopathy, concomitant preeclampsia was associated with worse 1-year event-free survival for death and hospital readmission (P=0.047).
Why the study?
Does preeclampsia impact clinical and functional outcomes in women with peripartum cardiomyopathy?
Population
39 women diagnosed with peripartum cardiomyopathy delivering at Barnes-Jewish Hospital between 2004 to 2014.
Comparison
Preeclampsia vs No preeclampsia
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
PPCM with preeclampsia warrants closer surveillance for adverse events; extends prior risk associations by showing differential LV remodeling and recovery.
Study Design
Type
Cohort (n=39)
Multicenter
No
Structured PICO
Does preeclampsia impact clinical and functional outcomes in women with peripartum cardiomyopathy?
P
Population
39 women with peripartum cardiomyopathy delivering at a single center between 2004 and 2014, followed for 1 year.
E
Exposure
Preeclampsia
C
Comparator
No preeclampsia
O
Outcome
One-year event-free survival rate for the combined end point of death and hospital readmissioncomposite
Main Result
p-value: p=0.047
In women with peripartum cardiomyopathy, concomitant preeclampsia is associated with worse 1-year event-free survival but a higher likelihood of left ventricular ejection fraction recovery among survivors.
Cite This Study
Lindley et al. (2017) conducted a cohort in Peripartum cardiomyopathy (n=39). Preeclampsia vs. No preeclampsia was evaluated on One-year event-free survival rate for the combined end point of death and hospital readmission (p=0.047). In women with peripartum cardiomyopathy, concomitant preeclampsia was associated with worse 1-year event-free survival for death and hospital readmission (P=0.047).