Plant-Derived Exosome-Like Nanoparticles Based Treatments In Cancer Therapy

Plant-derived exosome-like vesicles (PELVs) are nanometer-sized particles comprising proteins, lipids, nucleic acids, and small molecule substances generated from plants. PELVs have many advantages, such as low toxicity, efficient cellular uptake, high biocompatibility, stability, and large-scale production. PELVs can regulate intercellular communication by releasing their contents, including mRNA, miRNA, lipids, and proteins. Plant-derived exosome-like vesicles (PDELVs) have attracted considerable attention in scientific research owing to their promising therapeutic effects and researches have assessed the the extensive therapeutic potential of PDELVs in the treatment of various diseases including cancer treatment. They exhibit various clinical attributes and therapeutic benefits over conventional pharmaceuticals. This mini-review aims to summarize and categorize the main paths followed by scientists working with the PDELNs for cancer therapy.