Why the study?
Does PCR-based molecular detection improve the microbiological diagnosis of culture-negative infective endocarditis in surgically treated patients?
Case-Control (n=28)
No
Does PCR-based molecular detection improve the microbiological diagnosis of culture-negative infective endocarditis in surgically treated patients?
Absolute Event Rate: 93% vs 0%
PCR-based molecular testing of surgically excised heart valves provides fast, sensitive, and reliable pathogen identification in patients with culture-negative infective endocarditis.
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C.G. Sajeev (2003) conducted a case-control in Culture negative infective endocarditis (n=28). Polymerase chain reaction (PCR) based molecular methods vs. Patients without infective endocarditis was evaluated on PCR positivity for pathogens in valve samples.
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