January 1, 2000Molecular Human Reproduction

Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium

Q: What is the clinical evidence from this study?

Study design: Other. Population: Normal human endometrium. Intervention: Carbonic anhydrase XII expression analysis. Primary outcome: Expression and characterization of CA XII in human endometrium.

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Key result

Carbonic anhydrase XII is expressed in the basolateral plasma membrane of epithelial cells of normal human endometrium, suggesting a potential role in pH-dependent events preceding fertilization.

Authors

PKPepe KarhumaaUniversity of Oulu

Discussion

Member takes

Implication

No immediate clinical implications for fertility care; leaves open CA XII as a target in endometrial pH research.

PICO

Population

Normal human endometrium

Exposure / Comparator

Carbonic anhydrase XII expression analysis

Primary Outcome

Expression and characterization of CA XII in human endometrium

Cite This Study

Pepe Karhumaa (2000) studied Normal human endometrium. Carbonic anhydrase XII expression analysis was evaluated on Expression and characterization of CA XII in human endometrium. Carbonic anhydrase XII is expressed in the basolateral plasma membrane of epithelial cells of normal human endometrium, suggesting a potential role in pH-dependent events preceding fertilization.

synapsesocial.com/papers/6a96b75e6b29a448da82403e https://doi.org/10.1093/molehr/6.1.68

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