Key result
Exercise using the lower extremities increased the flow in the inferior vena cava from 48% to 75% of the total flow in normal subjects.
Why the study?
Does exercise using the lower extremities alter the distribution of venous return between the superior and inferior vena cava compared to rest in normal subjects?
Observational (n=10)
Does exercise using the lower extremities alter the distribution of venous return between the superior and inferior vena cava compared to rest in normal subjects?
Exercise significantly increases the proportion of venous return from the inferior vena cava, which is important for accurately calculating shunt size in patients with atrial septal defects.
Answers are grounded in this paper and cite their sources.
May require adjustment for increased IVC flow fraction during leg exercise in ASD shunt calculations; leaves open validation in patients with heart disease.
The relation between the flow in the superior vena cava and inferior vena cava has been measured on ten normal subjects both at rest and during exercise using the results of the oxygen saturation determinations on blood samples drawn from the pulmonary artery, superior vena cava and inferior vena cava. The result is that, with a doubling of the cardiac output caused by exercise using the lower extremities, the flow in the inferior vena cava is increased from 48% to 75% of the total flow. The importance of this for the calculation of the size of the shunt both at rest and during exercise in patients with atrial septal defects is discussed.
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Nielsen et al. (1968) conducted an observational in Healthy (n=10). Exercise using the lower extremities vs. Rest was evaluated on Flow in the inferior vena cava as a percentage of total flow. Exercise using the lower extremities increased the flow in the inferior vena cava from 48% to 75% of the total flow in normal subjects.
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