Key result
A middle-aged woman with chronic systemic lupus erythematosus developed an acute myocardial infarction caused by right coronary artery stenosis complicated by severe coronary artery spasm.
Why the study?
AMI is a major cause of death in SLE patients due to an increased CAD risk from chronic inflammation, involving diverse pathophysiologic mechanisms.
Case Report (n=1)
Clinicians should be aware of diverse pathophysiologic pathways, including coronary spasm, when managing acute myocardial infarction in patients with systemic lupus erythematosus.
Suggests spasm as possible MI trigger in SLE; hypothesis-generating and should not change practice.
Acute myocardial infarction (AMI) is a major cause of death in a patient with systemic lupus erythematosus (SLE). Due to their chronic inflammatory state, patient with SLE has an increased risk of developing coronary artery disease. We report a case of a middle-aged woman with an acute myocardial infarction (AMI) caused by a right coronary artery (RCA) stenosis complicated with severe coronary artery spasm. Our patient has a history of long-standing SLE. Clinical expression of coronary artery disease (CAD) in SLE is the result of different pathophysiologic mechanism. From this case, we raise the importance of the clinician to be aware of the diverse pathophysiologic pathways involving a coronary artery in a patient with SLE.
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Zhang et al. (2021) conducted a case report in Acute myocardial infarction, coronary spasm, systemic lupus erythematosus (n=1). Systemic lupus erythematosus was evaluated. A middle-aged woman with chronic systemic lupus erythematosus developed an acute myocardial infarction caused by right coronary artery stenosis complicated by severe coronary artery spasm.
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