Key result
Hemodialysis significantly increased mean QTc interval and QTc dispersion, with post-dialysis QTc dispersion >74 ms associated with significantly lower serum potassium and calcium.
Why the study?
Does hemodialysis affect QTc interval and QTc dispersion in hemodialysis patients?
Observational
Does hemodialysis affect QTc interval and QTc dispersion in hemodialysis patients?
Hemodialysis significantly prolongs QTc interval and increases QTc dispersion, likely driven by electrolyte shifts such as a fall in potassium and rise in calcium.
Post-dialysis QTc dispersion >74 ms associates with lower K/Ca; leaves open arrhythmia risk stratification and prospective validation needs.
= 0.424). Patients with post hemodialysis QTc dispersion >74 ms had significantly low mean values of serum potassium and calcium as compared to <74 ms group. Large numbers of hemodialysis patients have a prolonged QTc interval and QTc dispersion with a significant increase in the mean values after hemodialysis. There is a significant fall in serum potassium and rise in serum calcium after dialysis.
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Goel et al. (2018) conducted an observational in Hemodialysis. Hemodialysis vs. Pre-hemodialysis was evaluated on QTc interval and QTc dispersion. Hemodialysis significantly increased mean QTc interval and QTc dispersion, with post-dialysis QTc dispersion >74 ms associated with significantly lower serum potassium and calcium.
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